Anti-CHM Polyclonal Antibody,BR

英文名称:Anti-CHM Polyclonal Antibody
宿主:Rabbit
别名:DXS540;GGTA;HSD-32;REP-1;TCD
交叉反应:Human
应用:WB
稀释比例:WB 1:500-2000.
蛋白分子量:73/12kDa
Gene ID:1121
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human CHM
性状:液体
亚细胞定位:Cytoplasm cytosol
Swiss Prot:P24386
背景资料:This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene.
Public Immunogen Range:Recombinant protein of human CHM
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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