Anti-PIK3C2A Polyclonal Antibody,BR

英文名称:Anti-PIK3C2A Polyclonal Antibody
宿主:Rabbit
别名:CPK;PI3-K-C2(ALPHA);PI3-K-C2A;PI3K-C2-alpha;PI3K-C2alpha
交叉反应:Human Mouse Rat
应用:WB IHC IP
稀释比例:WB 1:500-2000. IHC 1:50-100. IP 1:50-100.
蛋白分子量:191kDa
Gene ID:5286
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human PIK3C2A
性状:液体
亚细胞定位:Cell membrane Cytoplasm Cytoplasmic vesicle Golgi apparatus Nucleus clathrin-coated vesicle
Swiss Prot:O00443
背景资料:The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.
Public Immunogen Range:Recombinant protein of human PIK3C2A
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意：
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