Anti-BCCIP Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-BCCIP Polyclonal Antibody
中文名称： 乳腺癌易感基因2和p21蛋白抑制因子抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:100-200.

抗体信息

靶标： BCCIP
别名： bccip, BCCIP_HUMAN, BCCIPalpha, BCCIPbeta, BRCA2 and CDKN1A interacting protein, BRCA2 and CDKN1A-interacting protein, BRCA2 and Cip1/p21 interacting protein, Cdk inhibitor p21 binding protein, P21 and CDK associated protein 1, P21- and CDK-associated protein 1, Protein TOK-1, Protein TOK1, TOK 1, TOK 1alpha, TOK 1beta, TOK1
背景说明： This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
Swiss Prot： Q9P287
Gene ID： 56647
亚细胞定位： Nucleus
免疫原： Recombinant protein of human BCCIP
Public Immunogen Range： 1-314aa
理论分子量： 36kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。