Anti-SPAG8 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-SPAG8 Polyclonal Antibody
中文名称： 精子相关抗原8抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse
应用： WB
稀释比例： WB 1:500-2000.

抗体信息

靶标： SPAG8
别名： BS-84;CILD28;CT142;HSD-1;SMP1;SPAG3;hSMP-1
背景说明： The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.
Swiss Prot： Q99932
Gene ID： 26206
亚细胞定位： Cytoplasm Cytoplasmic vesicle Cytoskeleton Nucleus
免疫原： Recombinant protein of human SPAG8
Public Immunogen Range： 220-420aa
理论分子量： 45kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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