Anti-RPE65 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-RPE65 Polyclonal Antibody
中文名称： 视网膜色素上皮细胞特异性蛋白65抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IF ; WB
稀释比例： WB 1:1000-5000. IF 1:50-200.

抗体信息

靶标： RPE65
别名： BCO3;LCA2;RP20;mRPE65;rd12;sRPE65
背景说明： This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa.
Swiss Prot： Q16518
Gene ID： 6121
亚细胞定位： Cell membrane Cytoplasm Lipid-anchor Microsome membrane
免疫原： Recombinant protein of human RPE65
Public Immunogen Range： 274-533aa
理论分子量： 61kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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