Anti-GAPDH Polyclonal Antibody,BR

英文名称:Anti-GAPDH Polyclonal Antibody
宿主:Rabbit
别名:G3PD;GAPD;HEL-S-162eP;GAPDH
稀释比例:WB 1:1000-10000. IHC 1:50-100. IF 1:20-50.
蛋白分子量:31/36kDa
Gene ID:2597
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human GAPDH
亚细胞定位:Cytoplasm Membrane Nucleus Cytoskeleton Cytosol Perinuclear region
Swiss Prot:P04406
背景资料:This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意：
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