Anti-Phospho-MAP3K7-S412 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-Phospho-MAP3K7-S412 Polyclonal Antibody
中文名称： 丝裂原活化蛋白激酶7抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： WB
稀释比例： WB 1:500-1000.

抗体信息

靶标： Phospho-MAP3K7-S412
别名： CSCF;FMD2;MEKK7;TAK1;TGF1a
背景说明： The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Swiss Prot： O43318
Gene ID： 6885
亚细胞定位： Cell membrane Cytoplasm Cytoplasmic side Peripheral membrane protein
免疫原： A phospho specific peptide corresponding to residues surrounding S412 of human MAP3K7
理论分子量： 54/57/64/67kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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