Anti-Phospho-ALK-Y1096 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-Phospho-ALK-Y1096 Polyclonal Antibody
中文名称： 间变型淋巴瘤激酶抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： WB
稀释比例： WB 1:500-2000.

抗体信息

靶标： Phospho-ALK-Y1096
别名： ALK tyrosine kinase receptor, ALK tyrosine kinase receptor precursor, ALK/EML4 fusion gene, included, ALK/NPM1 fusion gene, included, anaplastic lymphoma kinase (Ki-1), Anaplastic lymphoma kinase, Anaplastic lymphoma kinase Ki 1, Anaplastic lymphoma kinase Ki1, Anaplastic lymphoma kinase p80, CD 246, CD246, CD-246, CD246 antigen, EC 2.7.10.1, Ki 1, Ki1, NBLST3, Tcrz, TFG/ALK
背景说明： This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).
Swiss Prot： Q9UM73
Gene ID： 238
亚细胞定位： Cell membrane Single-pass type I membrane protein
免疫原： A phospho specific peptide corresponding to residues surrounding Y1096 of human ALK
理论分子量： 176kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。