Anti-Phospho-TNK2-Y284 Polyclonal Antibody,BR

英文名称:Anti-Phospho-TNK2-Y284 Polyclonal Antibody
宿主:Rabbit
别名:ACK;ACK-1;ACK1;p21cdc42Hs
交叉反应:Human
应用:WB
稀释比例:WB 1:500-2000.
蛋白分子量:115kDa
Gene ID:10188
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:A phospho specific peptide corresponding to residues surrounding Y284 of human TNK2
性状:液体
亚细胞定位:Cell junction Cell membrane Cytoplasmic side Cytoplasmic vesicle Cytoplasmic vesicle membrane Endosome Membrane Nucleus Peripheral membrane protein adherens junction clathrin-coated pit clathrin-coated vesicle
Swiss Prot:Q07912
背景资料:This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Public Immunogen Range:A phospho specific peptide corresponding to residues surrounding Y284 of human TNK2
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意：
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