Anti-MBP Monoclonal Antibody,BR

英文名称:Anti-MBP Monoclonal Antibody
别名:MGC99675;MBP

应用:ICC
稀释比例:WB 1:500-2000. IHC 1:200-1000. ICC 1:200-1000. FCM 1:200-400.
蛋白分子量:33kDa
Gene ID:4155
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG1
免疫原:Recombinant protein of human MBP
性状:液体
亚细胞定位:Cell membrane Membrane Nucleus
Swiss Prot:P02686
背景资料:The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.
Public Immunogen Range:Recombinant protein of human MBP
克隆类型:Monoclonal Antibody
规格:50ul, 100ul, 注意：
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