Anti-DTX3L Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-DTX3L Polyclonal Antibody
中文名称： E3泛素蛋白连接酶DTX3L抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： WB
稀释比例： WB 1:200-1000.

抗体信息

靶标： DTX3L
别名： B lymphoma and BAL associated protein, B-lymphoma- and BAL-associated protein, BBAP, Deltex 3 like, DTX 3L, DTX3L, DTX3L_HUMAN, E3 ubiquitin-protein ligase DTX3L, Protein deltex 3 like, Protein deltex 3 like protein, Protein deltex-3-like, Rhysin 2, Rhysin-2, Rhysin2
背景说明： The Deltex family is responsible for influencing Notch signaling and may regulate transcription through interactions with specific transcription factors. Deltex proteins have a basic N-terminus, a central proline-rich region and a C-terminal RING-type zinc finger domain, a motif often found in ubiquitin-protein isopeptide ligases (E3). The RING-type zinc finger domain binds two Zn2+ atoms and forms a cross-brace motif that is essential for many proteins involved the ubiquitination pathway. DTX3L (Deltex-3-like), also known as BBAP, is a 740 amino acid protein that is similar to Deltex-3 and acts as a ubiquitin ligase in vitro. DTX3L can heterodimerize with Deltex-1, a transcriptional regulator, thereby enhancing the activity of the E3 ubiquitin ligase complex and increasing the influence of E3 on the Notch signaling pathway.
Swiss Prot： Q8TDB6
Gene ID： 151636
亚细胞定位： Cytoplasm Endosome Lysosome Membrane Nucleus
免疫原： Recombinant protein of human DTX3L
理论分子量： 84kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。