Anti-ICOS Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ICOS Polyclonal Antibody
中文名称： 诱导协同刺激分子CD278抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC
稀释比例： IHC 1:10-100.

抗体信息

靶标： ICOS
别名： Activation inducible lymphocyte immunomediatory molecule, Activation-inducible lymphocyte immunomediatory molecule, AILIM, CD278, CD278 antigen, CVID1, ICOS, ICOS_HUMAN, Inducible costimulator, Inducible T cell co stimulator, Inducible T-cell costimulator, MGC39850
背景说明： The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
Swiss Prot： Q9Y6W8
Gene ID： 29851
亚细胞定位： Cell membrane Cytoplasm
免疫原： Recombinant protein of human ICOS
理论分子量： 23kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。