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Anti-EID1 Polyclonal Antibody,BR
Anti-EID1 Polyclonal Antibody
(订货以英文名为准)猜你喜欢
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产品属性 Product Attributes
基本信息
英文名称: Anti-EID1 Polyclonal Antibody中文名称: 乙酰基转移酶EID1抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Rat ; Mouse ; Human
应用: WB
稀释比例: WB 1:200-1000.
抗体信息
靶标: EID1别名: 21 kDa pRb associated protein, C15orf3, CBP, Chromosome 15 open reading frame 3, CREBBP/EP300 inhibitor 1, CREBBP/EP300 inhibitory protein 1, CRI 1, CRI1, E1A like inhibitor of differentiation, EID 1, EP300 interacting inhibitor of differentiation 1, NB4 apoptosis related protein, PNAS 22, PNAS22 , PTD014, Rb and p300 binding protein EID 1, Rb and p300 binding protein EID1, RBP21, Retinoblastoma protein associated protein, EID1_HUMAN
背景说明: E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
Swiss Prot: Q9Y6B2
Gene ID: 23741
亚细胞定位: Nucleus Cytoplasm
免疫原: Recombinant protein of human EID1
理论分子量: 19/21kDa
其它标识
纯化方法: Affinity purification储存液: pH7.4 PBS,0.05% NaN3,40% Glycerol.
储存条件: Store at -20℃. Avoid freeze / thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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