Anti-VRK1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-VRK1 Polyclonal Antibody
中文名称： 痘苗病毒相关激酶1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:25-100.

抗体信息

靶标： VRK1
别名： PCH1, Serine/threonine protein kinase VRK1, Serine/threonine-protein kinase VRK1, Vaccinia related kinase 1, Vaccinia virus B1R related kinase 1, Vaccinia-related kinase 1, VRK1, VRK1_HUMAN, MGC117401, MGC138280, MGC142070
背景说明： This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
Swiss Prot： Q99986
Gene ID： 7443
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human VRK1
理论分子量： 45kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

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