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Anti-APAF1 Polyclonal Antibody,BR
Anti-APAF1 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-APAF1 Polyclonal Antibody中文名称: 凋亡蛋白活性因子-1(N端)抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse ; Rat ; Human
应用: IHC ; WB
稀释比例: WB 1:200-1000. IHC 1:25-100.
抗体信息
靶标: APAF1别名: APAF 1, APAF1, CED4, DKFZp781B1145, KIAA0413
背景说明: This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
Swiss Prot: O14727
Gene ID: 317
亚细胞定位: Cytoplasm
免疫原: A synthetic peptide of human APAF1
理论分子量: 142kDa
其它标识
纯化方法: Affinity purification储存液: pH7.4 PBS,0.05% NaN3,40% Glycerol.
储存条件: Store at -20℃. Avoid freeze / thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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