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Anti-NPR1 Polyclonal Antibody,BR
Anti-NPR1 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-NPR1 Polyclonal Antibody中文名称: 利钠肽受体A抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Rat ; Mouse ; Human
应用: IHC
稀释比例: IHC 1: 25-100
抗体信息
靶标: NPR1别名: NPRA, ANP A, ANP-A, ANPa, ANPR-A, ANPRA, ANPRA_HUMAN, Atrial natriuretic peptide A type receptor, Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide receptor A, Atrial natriuretic peptide receptor type A, Atrionatriuretic peptide receptor A, GC A, GC-A, Guanylate cyclase A, Guanylate cyclase, GUC2A, GUCY2A, Natriuretic peptide A type receptor, Natriuretic peptide receptor A/guanylate cyclase A, NPR 1, NPR A, NPR-A, NPR1, NPRA
背景说明: Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms . The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).
Swiss Prot: P16066
Gene ID: 4881
亚细胞定位: Nucleus
免疫原: A synthetic peptide of human NPR1
理论分子量: 119kDa
其它标识
纯化方法: Affinity purification储存液: pH7.4 PBS,0.05% NaN3,40% Glycerol.
储存条件: Store at -20℃. Avoid freeze / thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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