Anti-MAPK8 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MAPK8 Polyclonal Antibody
中文名称： 磷酸化氨基末端激酶1/2/3抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:25-100.

抗体信息

靶标： MAPK8
别名： JNK;JNK1;PRKM8;SAPK1;JNK-46;JNK1A2;SAPK1c;JNK21B1/2
背景说明： The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Swiss Prot： P45983
Gene ID： 5599
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human MAPK8
理论分子量： 48kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

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