Anti-ARID1A Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ARID1A Polyclonal Antibody
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： ARID1A
别名： ELD;B120;OSA1;P270;hELD;BM029;MRD14;hOSA1;BAF250;C1orf4;BAF250a;SMARCF1
背景说明： This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions.
Swiss Prot： O14497
Gene ID： 8289
亚细胞定位： Nucleus
免疫原： A synthetic peptide of human ARID1A
理论分子量： 242/218/206kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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