Anti-HMGCS1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-HMGCS1 Polyclonal Antibody
中文名称： 三羟基三甲基辅酶A合成酶1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:50-200.

抗体信息

靶标： HMGCS1
别名： 3 hydroxy 3 methylglutaryl Coenzyme A synthase 1 (soluble), HMG CoA synthase, HMGCS, Hydroxymethylglutaryl CoA synthase, cytoplasmic, MGC90332: EC 2.3.3.10, HMCS1_HUMAN
背景说明： HMG-CoA Synthase exists as both a mitochondrial (mHMGCS) and cytoplasmic (cHMGCS) enzyme that condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The HMG-CoA produced by cHMGCS is transformed into mevalonate by HMG-CoA reductase, which starts isoprenoid biosynthesis. End products of the isoprenoid pathway include cholesterol, ubiquinone, dolichol, isopentenyl adenosine and farnesyl groups. mHMGCS, together with HMG-CoA Lyase, is responsible for ketone body biosynthesis. mHMGCS is expressed in liver and kidney. Fasting, cAMP and fatty acids increase the level of transcription of mHMGCS, while feeding and insulin repress it. A regulatory element within the mHMGCS promoter confers transcriptional regulation by PPAR, RXR, COUP-TF and HNF-4.
Swiss Prot： Q01581
Gene ID： 3157
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human HMGCS1
理论分子量： 57kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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