Anti-NPRL2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-NPRL2 Polyclonal Antibody
中文名称： GATOR复合体蛋白NPRL2抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： IHC ; WB
稀释比例： WB 1:200-1000. IHC 1:50-200.

抗体信息

靶标： NPRL2
别名： G21 protein, Gene 21 protein, Homologous to yeast nitrogen permease (candidate tumor suppressor), Homologous to yeast nitrogen permease, NPR 2L, NPR L2, NPR like 2, NPR2 like, NPRL 2, NPRL2, Tumor suppressor candidate 4, TUSC 4, TUSC 4 protein, TUSC4, TUSC4 protein, NPRL2_HUMAN
背景说明： NPRL2, also known as TUSC4 (tumor suppressor candidate 4), is a 380 amino acid protein that contains a bipartite nuclear localization signal and a granulin protein-binding domain. It is highly expressed in skeletal muscle, followed by brain, liver and pancreas, with lower expression in lung, kidney, placenta and heart. NPRL2 is also expressed in most lung cancer cell lines and may be involved in tumor suppression. NPRL2 may play a role in mismatch repair, cell cycle checkpoint signaling and activation of apoptotic pathways. It may also enhance the therapeutic efficacy of chemotherapy drugs such as cis-platin by resensitizing patients resistant to cisplatin treatment. The gene encoding NPRL2 is conserved between species and is expressed as two isoforms due to alternative splicing events.
Swiss Prot： Q8WTW4
Gene ID： 10641
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human NPRL2
理论分子量： 44kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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