- 首页
- Anti-SRGAP1 Polyclonal Antibody,BR
Anti-SRGAP1 Polyclonal Antibody,BR
Anti-SRGAP1 Polyclonal Antibody
(订货以英文名为准)猜你喜欢
CAS No:70264-94-7
CAS No:9004-74-4
CAS No:14808-60-7
CAS No:115383-22-7
CAS No:652-03-9
CAS No:93427-13-5
CAS No:5852-78-8
CAS No:25322-68-3
CAS No:78081-87-5
CAS No:6968-22-5
产品属性 Product Attributes
基本信息
英文名称: Anti-SRGAP1 Polyclonal Antibody中文名称: SLIT-ROBO Rho GTP酶激活蛋白1抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Mouse
应用: IHC ; WB
稀释比例: WB 1:2000-5000. IHC 1:25-100.
抗体信息
靶标: SRGAP1别名: ARHGAP13, FLJ22166, KIAA1304, RGD1566260, Rho GTPase activating protein 13, SLIT ROBO Rho GTPase activating protein 1, SRGAP 1, SRGP1_HUMAN
背景说明: SRGAP1 contains an FCH (Fes/CIP4 homology) domain, a Rho-GAP domain and an SH3 domain. In the presence of Slit, SRGAP1 (via its SH3 domain) binds to the CC3 motif in robo (a protein responsible for mediating the repulsive effect of Slit) with higher affinity and inhibits Cdc42 activity in a robo/SRGAP-dependent manner. More specifically, SRGAP1 increases the intrinsic GTPase activity of Cdc42, thereby converting it to its inactive, GDP-bound form. Inactivation of Cdc42 ultimately leads to a decrease in actin polymerization.
Swiss Prot: Q7Z6B7
Gene ID: 57522
亚细胞定位: Cytoplasm Nucleus
免疫原: A synthetic peptide of human SRGAP1
理论分子量: 124kDa
其它标识
纯化方法: Affinity purification储存液: pH7.4 PBS,0.05% NaN3,40% Glycerol.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
沪公网安备31012002005909号
点击QQ联系