Anti-NLRP3 Polyclonal Antibody,BR

英文名称:Anti-NLRP3 Polyclonal Antibody
宿主:Rabbit
别名:NLRP3;AGTAVPRL;AII;AVP;C1orf7;CIAS1;CLR1.1;FCAS;FCAS1;FCU;MWS;NALP3;PYPAF1;NLR family pyrin domain containing 3

交叉反应:Human Mouse Rat
应用:WB
稀释比例:WB 1:200-1000.
蛋白分子量:118/105/83/112kDa
Gene ID:114548
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human NLRP3
性状:液体
亚细胞定位:Nucleus Cytoplasm Secreted
Swiss Prot:Q96P20
背景资料:This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.
Public Immunogen Range:Recombinant protein of human NLRP3
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意：
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