Anti-GREM1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-GREM1 Polyclonal Antibody
中文名称： 骨形态形成蛋白拮抗蛋白抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： WB
稀释比例： WB 1:500-2000.

抗体信息

靶标： GREM1
别名： DRM;HMPS;MPSH;PIG2;CRAC1;CRCS4;DAND2;HMPS1;IHG-2;DUP15q;C15DUPq;GREMLIN;CKTSF1B1
背景说明： This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： O60565
Gene ID： 26585
亚细胞定位： Secreted
免疫原： Recombinant protein of human GREM1
理论分子量： 21kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。