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Anti-GRK4 Polyclonal Antibody,BR
Anti-GRK4 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-GRK4 Polyclonal Antibody中文名称: G蛋白偶联受体激酶4抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human
应用: ELISA ; IHC ; WB
稀释比例: WB 1:500-2000. IHC 1:50-200. ELISA 1:5000-10000.
抗体信息
靶标: GRK4别名: G protein coupled receptor kinase 4, G protein-coupled receptor kinase 2 (Drosophila)-like, G protein-coupled receptor kinase 4, G protein-coupled receptor kinase GRK4, G proteinm coupled receptor kinase GRK4, GPRK2L, GPRK4, GRK4, GRK4_HUMAN, GRK4a, ITI1
背景说明: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin; the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2.
Swiss Prot: P32298
Gene ID: 2868
亚细胞定位: Cytoplasm
免疫原: Recombinant protein of human GRK4
理论分子量: 67kDa
其它标识
纯化方法: Affinity purification储存液: pH7.4 PBS,0.05% NaN3,40% Glycerol.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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