Anti-DOK4 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-DOK4 Polyclonal Antibody
中文名称： 衔接蛋白4抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:10-100.

抗体信息

靶标： DOK4
别名： docking protein 4, Downstream of tyrosine kinase 4, FLJ10488, DOK4_HUMAN
背景说明： Docking protein 4 is a protein that in humans is encoded by the DOK4 gene. Dok-4 is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.
Swiss Prot： Q8TEW6
Gene ID： 55715
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human DOK4
理论分子量： 37kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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