Anti-CDK2AP1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CDK2AP1 Polyclonal Antibody
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： IHC
稀释比例： IHC 1:25-100.

抗体信息

靶标： CDK2AP1
别名： DOC1,ST19,DORC1,doc-1,p12DOC-1,CDK2AP1,CDKAP1,CDKA1_HUMAN,cyclin-dependent kinase 2-associated protein 1
背景说明： The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Swiss Prot： O14519
Gene ID： 8099
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human CDK2AP1
理论分子量： 12kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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