Anti-MAPK10 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MAPK10 Polyclonal Antibody
中文名称： 有丝分裂原活化蛋白激酶10抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:5-20.

抗体信息

靶标： MAPK10
别名： JNK3;JNK3A;PRKM10;SAPK1b;p493F12;p54bSAPK
背景说明： The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Swiss Prot： P53779
Gene ID： 5602
亚细胞定位： Cytoplasm Lipid-anchor Membrane Mitochondrion Nucleus
免疫原： A synthetic peptide of human MAPK10
理论分子量： 53kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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