Anti-VPS36 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-VPS36 Polyclonal Antibody
中文名称： 液泡蛋白分选蛋白36抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC ; WB
稀释比例： WB 1:200-1000.IHC 1:25-100.

抗体信息

靶标： VPS36
别名： C13orf9, CGI 145, EAP45, ELL associated protein of 45 kDa, ELL-associated protein of 45 kDa, ESCRT-II complex subunit VPS36, Vacuolar protein sorting associated protein 36, Vacuolar protein-sorting-associated protein 36, Vps36, VPS36_HUMAN
背景说明： Vacuolar sorting proteins (VPSs) are required for trafficking normal endocytic and biosynthetic proteins to the vacuole and also play an important role in the budding process of cells. The ESCRT-II (endosomal sorting complex required for transport II) complex, which is involved in endocytosis of ubiquinated membrane proteins, is formed by Eap45, EAP30, and VPS25. These vacuolar sorting proteins are also involved in a multiprotein complex with RNA ploymerase II elongation factor (ELL). Eap45 (ELL-associated protein of 45 kDa), also known as vacuolar protein-sorting-associated protein 36, is a 386 amino acid protein containing a GLUE (GRAM-like ubiquitin-binding in Eap45) domain that mediates the binding to ubiquitin and phophoinosides. Since Eap45 colocalizes with ubiquinated proteins on late endosomes, it is likely that Eap45 plays a role in the endosomal sorting of ubiquniated cargo. There are two isoforms of Eap45 that exist as a result of alternative splicing events.
Swiss Prot： Q86VN1
Gene ID： 51028
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human VPS36
理论分子量： 44kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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