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Anti-DDR2 Monoclonal Antibody,BR
Anti-DDR2 Monoclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-DDR2 Monoclonal Antibody中文名称: 盘状结构域受体蛋白2抗体
规格: 50ul ; 100ul
宿主: Mouse
克隆类型: Monoclonal Antibody
亚型: IgG1克隆号 1E9A10
交叉反应:: Human
应用: ELISA ; WB
稀释比例: WB 1:1000-6000.
抗体信息
靶标: DDR2别名: DDR2;Discoidin domain receptor 2;MIG20a;NTRKR3;TKT;TYRO10;Tyrosine protein kinase TYRO10
背景说明: Tyrosine kinase involved in the regulation of tissues remodeling (PubMed:30449416). It functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.
Swiss Prot: Q16832
Gene ID: 4921
亚细胞定位: Cell membrane
免疫原: Recombinant protein of human DDR2
Public Immunogen Range: 291-398aa
理论分子量: 97kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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