Anti-MOG Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MOG Polyclonal Antibody
中文名称： 髓鞘少树突胶质细胞糖蛋白抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse预测
交叉反应：： Human;Pig;Guinea Pig
应用： ELISA ; IF ; ICC ; IHC ; WB
稀释比例： WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. ICC 1:100-500. IF 1:100-500.

抗体信息

靶标： MOG
别名： MOG(35-55);myelin oligo-dendrocyte glycoprotein-MOG;MGC26137;MOG alpha 6;MOG;MOGIG2;Myelin oligodendrocyte glycoprotein;
背景说明： The protein is a key CNS-specific autoantigen for primary demyelination in multiple sclerosis. Although the disease-inducing role of MOG has been established, its precise function in the CNS remains obscure. MOG is a type I integral membrane protein possessing a single extracellular Ig variable domain (Ig-V) (3, 13, 14). The amino acid sequence of MOG is highly conserved among animal species (>90%), indicative of an important biological function. MOG is specifically expressed in the CNS on the outermost lamellae of the myelin sheath as well as the cell body and processes of oligodendrocytes. The developmentally late expression of MOG correlates with the later stages of myelinogenesis, suggesting that MOG has a role in the completion, compaction, and/or maintenance of myelin, further suggesting that MOG has an adhesive function within the CNS . Consistent with MOG's possible adhesive role in the CNS, a homodimeric form of MOG has not only been observed after isolation from the CNS but has additionally been observed in situ.
Swiss Prot： Q61885
Gene ID： 17441
亚细胞定位： Cytomembrane
免疫原： A synthetic peptide of human MOG
Public Immunogen Range： 35-55/247aa
理论分子量： 24kDa

其它标识

纯化方法： Affinity purification
储存液： 0.01M TBS(pH7.4) with 1% BSA，0.03% Proclin300 and 50% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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