Anti-GCK Monoclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-GCK Monoclonal Antibody
中文名称： 葡萄糖激酶抗体
规格： 50ul ; 100ul
宿主： Mouse
克隆类型： Monoclonal Antibody
亚型： IgG1
交叉反应：： Pig ; Rat ; Human ; Mouse
应用： ELISA ; IF ; IHC ; WB
稀释比例： WB 1:5000-20000. IHC 1:300-1000. IF 1:200-800.

抗体信息

靶标： GCK
别名： GCK;GK, GLK;Glucokinase;glucokinase (hexokinase 4);Hexokinase 4;Hexokinase D;Hexokinase type IV;HHF3;HK IV;HK4;HKIV;HXKP;MODY2
背景说明： Glucokinase (GCK) is a structurally and functionally unique member of hexokinase family. It is expressed only in mammalian liver and pancreatic islet beta cells. Because of its unique functional characteristics, the enzyme plays an important regulatory role in glucose metabolism.The rate of glucose metabolism in liver and pancreas is a function of the activity of the enzyme(PMID:1740341). Moreover, GCK has been found to have relationship with diabetes. Defects in GCK are the cause of maturity-onset diabetes of the young type 2 (MODY2) and familial hyperinsulinemic hypoglycemia type 3 (HHF3). It has 3 isoforms produced by alternative splicing with the same molecular mass of 52 kDa.
Swiss Prot： P35557
Gene ID： 2645
亚细胞定位： Cytoplasm Mitochondrion Nucleus
免疫原： Recombinant protein of human GCK
Public Immunogen Range： 157-465aa
理论分子量： 52kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。