Anti-Caspase 3/P17/P19 Monoclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-Caspase 3/P17/P19 Monoclonal Antibody
中文名称： 胱天蛋白酶3抗体
规格： 50ul ; 100ul
宿主： Mouse
克隆类型： Monoclonal Antibody
亚型： IgG1
交叉反应：： Rat ; Mouse ; Human
应用： ELISA ; IF ; IHC ; WB
稀释比例： WB 1:1000-3000. IHC 1:150-600. IF 1:50-500.

抗体信息

靶标： Caspase 3/P17/P19
别名： Apopain;CASP 3;CASP3;Caspase 3;Caspase3;Caspase-3;CPP 32;CPP32;CPP32B;Cysteine protease CPP32;Protein Yama;SCA 1;SREBP cleavage activity 1
背景说明： Caspases, a family of endoproteases, are critical players in cell regulatory networks controlling inflammation and cell death. Initiator caspases (caspase-2, -8, -9, -10, -11, and -12) cleave and activate downstream effector caspases (caspase-3, -6, and -7), which in turn execute apoptosis by cleaving targeted cellular proteins. Caspase 3 (also named CPP32, SCA-1, and Apopain) proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at the beginning of apoptosis. Caspase 3 plays a key role in the activation of sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Caspase 3 can also form heterocomplex with other proteins and performs the molecular mass of 50-70 kDa. This antibody can recognize p17, p19 and p32 of Caspase 3.
Swiss Prot： P42574
Gene ID： 836
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human Caspase 3/p17/p19
Public Immunogen Range： 31-176aa
理论分子量： 32kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。