Anti-BAX Monoclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-BAX Monoclonal Antibody
中文名称： Bcl2关联X蛋白抗体
规格： 50ul ; 100ul
宿主： Mouse
克隆类型： Monoclonal Antibody
亚型： IgG2b
交叉反应：： Rat ; Mouse ; Human
应用： ELISA ; FCM ; IHC ; WB
稀释比例： WB 1:5000-20000. IHC 1:500-2000.

抗体信息

靶标： BAX
别名： ax zeta,Bax-protein,Bcl-2-like protein 4,BCL2 associated X protein,BCL2L4,BAX_HUMAN,Bcl2-L-4
背景说明： BAX, also named as BCL2L4, is a pro-apoptotic member of the Bcl-2 protein family, which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells, but accumulates on the outer mitochondrial membrane upon apoptosis induction. BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane, which leads to the release of cytochrome c from mitochondria. The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis.
Swiss Prot： Q07812
Gene ID： 581
亚细胞定位： Mitochondrion
免疫原： Recombinant protein of human BAX
Public Immunogen Range： 1-192aa
理论分子量： 21kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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