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Anti-SOCS7 Polyclonal Antibody,BR
Anti-SOCS7 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-SOCS7 Polyclonal Antibody中文名称: 信号转导和转录激活因子7抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Rat ; Mouse ; Human预测
交叉反应:: Rabbit
应用: ELISA ; IF ; ICC ; IHC ; WB
稀释比例: WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. ICC 1:100-500. IF 1:100-500.
抗体信息
靶标: SOCS7别名: NAP 4;NAP 4 Fragment;NAP4;Nck Ash and phospholipase C binding protein;Nck Ash and phospholipase C gamma binding protein;Nck associated protein 4;NCKAP4;SH2 domain containing SOCS box protein;SOCS 7;SOCS4;SOCS6;Suppressor of cytokine signaling 7
背景说明: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Swiss Prot: O14512
Gene ID: 30837
亚细胞定位: Cell membrane Cytoplasm
免疫原: A synthetic peptide of human SOCS7
Public Immunogen Range: 171-270/581aa
理论分子量: 63kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.03% Proclin300,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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