Anti-PARP Polyclonal Antibody,BR

英文名称:Anti-PARP Polyclonal Antibody
宿主:Rabbit
别名:ADP ribosyltransferase (NAD+;poly (ADP ribose) polymerase);ADP ribosyltransferase NAD+;ADPRT 1;ADPRT;ADPRT1;msPARP;NAD(+) ADP ribosyltransferase 1;pADPRT 1;pADPRT1;PARP 1;PARP1;Poly (ADP ribose) polymerase 1;poly (ADP ribose) polymerase family, member 1;Poly adenosine diphosphate ADP ribose polymerase;Poly ADP ribose polymerase 1;Poly ADP ribose polymerase family member 1;Poly ADP ribose synthetase 1;poly(ADP ribose) synthetase;poly(ADP ribosyl)transferase;Poly[ADP ribose] synthetase 1;PPOL;sPARP 1;sPARP1
交叉反应:Human Mouse Rat Dog Cow
应用:WB ELISA IHC-P IHC-F Flow-Cyt IF
稀释比例:WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. Flow-Cyt 0.2μg/Test. IF 1:100-500.
蛋白分子量:116kDa
Gene ID:142
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:KLH conjugated synthetic peptide derived from human PARP
亚细胞定位:Cytoplasm Nucleus matrix Nucleus membrane Peripheral membrane protein
Swiss Prot:P09874
背景资料:Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly(ADP-ribosyl)ation of APLF and CHFR. Positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. With EEF1A1 and TXK, forms a complex that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意：
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