Anti-MAP1LC3B Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MAP1LC3B Polyclonal Antibody
中文名称： 微管相关蛋白1轻链3β抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rabbit ; Rat ; Mouse ; Human预测
交叉反应：： Chicken;Dog;Pig;Cow;Horse
应用： ELISA ; IF ; IHC
稀释比例： ELISA 1:5000-10000. IHC 1:100-500. IF 1:100-500.

抗体信息

靶标： MAP1LC3B
别名： Microtubule-associated protein 1 light chain 3 beta,ATG8F, Autophagy related protein LC3 B, Autophagy related ubiquitin like modifier LC3 B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3 like protein 2, MAP1 light chain 3-like protein 2, MAP1A/1B light chain 3 B, MAP1A/1BLC3, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 B, MAP1ALC3, MAP1LC3B, Microtubule associated protein 1 light chain 3 beta, Microtubule associated proteins 1A/1B light chain 3B, Microtubule-associated protein 1 light chain 3 beta, Microtubule-associated proteins 1A/1B light chain 3B, MLP3B_HUMAN
背景说明： A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy.
Swiss Prot： Q9GZQ8
Gene ID： 81631
亚细胞定位： Cytoplasm Cytoplasmic vesicle Endomembrane system Lipid-anchor autophagosome autophagosome membrane cytoskeleton
免疫原： A synthetic peptide of human MAP1LC3B
Public Immunogen Range： 21-121/121aa
理论分子量： 15kDa

其它标识

纯化方法： Affinity purification
储存液： 0.01M TBS(pH7.4) with 1% BSA，0.03% Proclin300 and 50% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。