Anti-PHD2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PHD2 Polyclonal Antibody
中文名称： egl nine同源蛋白C抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human预测
交叉反应：： Pig;Cow;Rabbit
应用： ELISA ; IF ; IHC ; WB
稀释比例： WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. IF 1:100-500.

抗体信息

靶标： PHD2
别名： SM 20, Zinc finger MYND domain containing protein 6, C1ORF12, Chromosome 1 Open Reading Frame 12, ECYT 3, ECYT3, EGL 9 homolog of C. elegans 1, EGL nine (C.elegans) homolog 1, Egl nine homolog 1, Egl nine like protein 1, EGLN 1, EGLN1, HIF PH2, HIF Prolyl Hydroxylase 2, HIFP4H 2, HIFPH2, HPH 2, HPH2, Hypoxia inducible factor prolyl hydroxylase 2, ORF13, P4H2, PHD 2, PHD2, PNAS 118, PNAS 137, Prolyl Hydroxylase Domain Containing Protein 2, Rat Homolog of SM20, SM20, ZMYND6
背景说明： PHD2 protein catalyzes the posttranslational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. In the presence of oxygen, PHD2 converts specific prolyl residues in HIF alpha to hydroxyproline, leading to HIF alpha proteasomal degradation via the von Hippel-Lindau ubiquitylation complex. Low oxygen levels, sensed at the cellular level, cause the HIF conversion to be reduced so that HIF levels are stable. This results in increased angiogenesis as HIF1 alpha regulates the expression of many angiogenesis-related genes.
Swiss Prot： Q9GZT9
Gene ID： 54583
亚细胞定位： Cytoplasm Nucleus
免疫原： A synthetic peptide of human PHD2
Public Immunogen Range： 42-140/426aa
理论分子量： 36/43/46kDa

其它标识

纯化方法： Affinity purification
储存液： 0.01M TBS(pH7.4) with 1% BSA，0.03% Proclin300 and 50% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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