Anti-IGF1R Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-IGF1R Polyclonal Antibody
中文名称： 胰岛素样蛋白生长因子1受体抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human预测
交叉反应：： Rat;Pig;Cow;Sheep
应用： ELISA ; FCM ; IF ; ICC ; IHC ; WB
稀释比例： WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1μg/Test. ICC 1:100. IF 1:100-500.

抗体信息

靶标： IGF1R
别名： CD221,CD221 antigen,IGF1 Receptor,IGF 1 receptor,IGF 1R,IGF I receptor,IGF1R,IGFIR,IGFIRC, JTK13,MGC142170,MGC142172,IGF 1 receptor,IGF-1R,IGF I receptor,IGF-I receptor,IGF-IR,IGF-I Receptor β
背景说明： This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.
Swiss Prot： P08069
Gene ID： 3480
亚细胞定位： Cell membrane
免疫原： A synthetic peptide of human IGF1R
Public Immunogen Range： 821-920/1367aa
理论分子量： 69/150kDa

其它标识

纯化方法： Affinity purification
储存液： 0.01M TBS(pH7.4) with 1% BSA，0.03% Proclin300 and 50% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。