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Anti-INSR Polyclonal Antibody,BR
Anti-INSR Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-INSR Polyclonal Antibody中文名称: 胰岛素受体α抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Rat ; Mouse ; Human预测
交叉反应:: Chicken;Dog;Cow;Horse;Rabbit;Sheep
应用: ELISA ; FCM ; IF ; IHC ; WB
稀释比例: WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1ug/Test. IF 1:100-500.
抗体信息
靶标: INSR别名: CD 220;CD220;CD220 antigen;HHF 5;HHF5;INSR;IR;INSR_HUMAN;Insulin receptor subunit alpha
背景说明: The insulin receptor is a heterotetrameric membrane glycoprotein with tyrosine-protein kinase activity, consisting of disulfide-linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit possesses a single transmembrane domain, whereas the alpha subunit is completely extracellular. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Binding of insulin to the insulin receptor stimulates its association with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K) which leads to glucose uptake. Two transcript variants encoding different isoforms have been found for this gene produced by alternative splicing.
Swiss Prot: P06213
Gene ID: 3643
亚细胞定位: Cytoplasm Cell membrane
免疫原: A synthetic peptide of human INSR
Public Immunogen Range: 51-150/1384aa
理论分子量: 156kDa
其它标识
纯化方法: Affinity purification储存液: 0.01M TBS(pH7.4) with 1% BSA,0.03% Proclin300 and 50% Glycerol.
储存条件: Store at -20℃. Avoid freeze / thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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