Anti-Mki67 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-Mki67 Polyclonal Antibody
规格： 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse
应用： IF ; IHC
稀释比例： IHC 1:500-1200. IF 1:500-1200.

抗体信息

靶标： Mki67
别名： Antigen identified by monoclonal antibody Ki 67,Antigen identified by monoclonal antibody Ki-67,Antigen KI-67,Antigen KI67,Antigen Ki67,KI67_HUMAN,KIA,Marker of proliferation Ki-67,MIB 1,MIB,MKI67,PPP1R105,Proliferation marker protein Ki-67,Proliferation related Ki 67 antigen,Protein phosphatase 1 regulatory subunit 105,MKI67,KIA,MIB-,MIB-1,PPP1R105,marker of proliferation Ki-67,Ki67
背景说明： Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (By similarity). Does not contribute to the internal structure of mitotic chromosomes (PubMed:26949251). May play a role in chromatin organization (PubMed:26949251). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed.
Swiss Prot： E9PVX6
Gene ID： 17345
亚细胞定位： Nucleus
免疫原： A synthetic peptide of mouse Ki67
理论分子量： 325/351kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，100 μg/ml BSA and 50% glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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