Anti-phospho-PI3KCA (Tyr317) Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-phospho-PI3KCA (Tyr317) Polyclonal Antibody
中文名称： 磷酸化磷脂酰肌醇激酶催化亚单位A抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human预测
交叉反应：： Rat
应用： ELISA ; IF ; IHC ; WB
稀释比例： WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. IF 1:100-500.

抗体信息

靶标： phospho-PI3KCA (Tyr317)
别名： PIK3CA(phospho Y317); PI3 kinase p110 subunit alpha; caPI3K; MGC142161; MGC142163; p110 alpha; p110 alpha
背景说明： PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdInsP2. Four isoforms of p110 has been found; alpha, beta, gamma, and the delta subunit. The alpha isoform, also known as PI3KCA, is a transforming oncogene that was shown to have activating mutations in nine types of cancers such as colon, brain, breast and stomach.
Swiss Prot： P42336
Gene ID： 5290
亚细胞定位： Cytoplasm Membrane
免疫原： A synthetic peptide of human PI3KCA around the phosphorylation site of Tyr317
理论分子量： 117kDa

其它标识

纯化方法： Affinity purification
储存液： 0.01M TBS(pH7.4) with 1% BSA，0.03% Proclin300 and 50% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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