Anti-SHP-2 Monoclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-SHP-2 Monoclonal Antibody
中文名称： 蛋白酪氨酸磷酸酶2抗体
规格： 100ul
宿主： Rabbit
克隆类型： Monoclonal antibody
亚型： IgG
交叉反应：： Human ; Monkey ; Rat ; Mouse
应用： IHC ; WB ; IP
稀释比例： WB 1:500-2000. IHC 1:50. IP 1:50.

抗体信息

靶标： SHP-2
别名： BPTP3;CFC;JMML;METCDS;NS1;PTP-1D;PTP2C;SH-PTP2;SH-PTP3;SHP2;PTPN11
背景说明： The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： Q06124
Gene ID： 5781
亚细胞定位： Cytoplasm
免疫原： A synthesized peptide derived from human SHP-2
理论分子量： 53/68kDa

其它标识

纯化方法： Affinity purification
储存液： Supplied in 10 mM sodium HEPES (pH 7.5)，150 mM NaCl，100 μg/ml BSA，50% glycerol and less than 0.02% sodium azide.
储存条件： Store at -20℃. Do not aliquot the antibody.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。