Anti-EMR1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-EMR1 Polyclonal Antibody
中文名称： 粘附G蛋白偶联受体E1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： ELISA ; IF ; IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:400-1600. IF 1:50-500.

抗体信息

靶标： EMR1
别名： ADGRE1, Adhesion G protein-coupled receptor E1, EGF like module receptor 1, EMR1, EMR1 hormone receptor, F4/80, TM7LN3
背景说明： EMR1 (EGF-like module containing mucin-like hormone receptor 1), also known as Adhesion G protein-coupled receptor E1 (ADGRE1), is a surface receptor with seven transmembrane segments that belongs to the EGF-7-transmembrane family of G protein-coupled receptors (PMID: 14647991, 7601460). EMR1 expression is restricted to eosinophilic granulocytes, where expression is overlapping with the eotaxin receptor CCR3 and the immunoglobulin-like lectin Siglec-8. Absence on other leukocytes, including basophils, implies that EMR1 is a highly specific marker for eosinophils in humans and may be used as a novel therapeutic target for eosinophilic disorders(PMID: 17823986, 24530099). F4/80, the murine homolog of EMR1, is a marker of murine macrophage. The apparent molecular weigh of F4/80 is 160 kDa, which is lager than the calculated molecular weight due to post-translational modifications (PMID: 7308288; 8647179).
Swiss Prot： Q14246
Gene ID： 2015
亚细胞定位： Cell membrane Multi-pass membrane protein
免疫原： Recombinant protein of human EMR1
Public Immunogen Range： 430-510aa
理论分子量： 90kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。