Anti-STX5 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-STX5 Polyclonal Antibody
中文名称： 突触融合蛋白5抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： ELISA ; IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:50-200. ELISA 1:5000-10000.

抗体信息

靶标： STX5
别名： SED5, STX5, STX5A, syntaxin 5
背景说明： The membrane protein syntaxin 5 (STX5) is a key component of soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) complexes that regulate cellular protein transport, vesicle docking, and membrane fusion. Syntaxin 5 protein is found as a 42 kDa (long) protein localized to the Golgi complex and endoplasmic reticulum, and a “short” 35 kDa isoform localized primarily to the Golgi. Formation of the syntaxin 5 SNARE complex, which also includes proteins Sec22B, Bet1, GOSR1, GOSR2, and Ykt6, allows for regulation of ER-to-Golgi transport, intra-Golgi transport, and endosome-to-Golgi retrograde transport. Research studies indicate that the syntaxin 5 SNARE complex also plays an essential role in autophagy following autophagosome formation. Intracellular protein transport mediated by the syntaxin 5 complex is required for transport and localized activity of lysosomal proteases. The experimental reduction or deletion of syntaxin 5 complex components results in non-functional lysosomes and accumulation of autophagosomes.
Swiss Prot： Q13190
Gene ID： 6811
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human STX5
理论分子量： 40 kDa

其它标识

纯化方法： Affinity Purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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