Anti-LFNG Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-LFNG Polyclonal Antibody
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： ELISA ; IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:50-200. ELISA 1:5000-10000.

抗体信息

靶标： LFNG
别名： LFNG,Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe,O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
背景说明： This gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the MFNG (GeneID: 4242) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3.
Swiss Prot： Q8NES3
Gene ID： 3955
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human LFNG
理论分子量： 42 kDa

其它标识

纯化方法： Affinity Purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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