Anti-NR3C1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-NR3C1 Polyclonal Antibody
中文名称： 核受体亚家族3,C组成员1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human预测
交叉反应：： Chimpanzee;Guinea pig;Monkey
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： NR3C1
别名： GCCR;GCR;GCRST;GR;GRL;glucocorticoid receptor
背景说明： Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth.
Swiss Prot： P04150
Gene ID： 2908
亚细胞定位： Cytoplasm Mitochondrion Nucleus Nucleus
免疫原： A synthetic peptide of human NR3C1
Public Immunogen Range： 30-80/777aa
理论分子量： 52/76/61/65/82/86kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。