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Anti-PDX1 Polyclonal Antibody,BR
Anti-PDX1 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-PDX1 Polyclonal Antibody中文名称: 胰岛素促进因子/胰十二指肠同源异型盒蛋白抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Rat ; Mouse预测
交叉反应:: Chimpanzee;Hamster
应用: WB ; IHC
稀释比例: WB 1:2000-5000.IHC 1:50-200.
抗体信息
靶标: PDX1别名: GSF;IDX-1;IPF1;IUF1;MODY4;PAGEN1;PDX-1;STF-1
背景说明: Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.
Swiss Prot: P52945
Gene ID: 3651
亚细胞定位: Cytoplasm Nucleus cytosol
免疫原: A synthetic peptide of human PDX1
Public Immunogen Range: 35-85/283aa
理论分子量: 31Da
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。


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