Anti-P4HB Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-P4HB Polyclonal Antibody
中文名称： 蛋白质二硫键异构酶抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human预测
交叉反应：： Monkey;Cow;Hamster;Rabbit;Chimpanzee
应用： WB ; IHC
稀释比例： WB 1:8000-12000. IHC 1:50-200.

抗体信息

靶标： P4HB
别名： CLCRP1;DSI;ERBA2L;GIT;P4Hbeta;PDI;PDIA1;PHDB;PO4DB;PO4HB;PROHB
背景说明： This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP.
Swiss Prot： P07237
Gene ID： 5034
亚细胞定位： Cell membrane Endoplasmic reticulum Endoplasmic reticulum lumen Melanosome Peripheral membrane protein
免疫原： A synthetic peptide of human P4HB
Public Immunogen Range： 80-130/508aa
理论分子量： 57kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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