Anti-Kir6.2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-Kir6.2 Polyclonal Antibody
中文名称： ATP敏感性钾通道亚基kir6.2抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human预测
交叉反应：： Chimpanzee;Pig;Opossums;Guinea pig
应用： WB
稀释比例： WB 1:5000-8000.

抗体信息

靶标： Kir6.2
别名： KCNJ11,BIR,HHF2,IKATP,MODY13,PHHI,TNDM3,ATP-sensitive inward rectifier potassium channel 11
背景说明： Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Swiss Prot： Q14654
Gene ID： 3767
亚细胞定位： Cell membrane
免疫原： A synthetic peptide of human Kir6.2
Public Immunogen Range： 340-390/390aa
理论分子量： 44/33kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。