Anti-NR1H4 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-NR1H4 Polyclonal Antibody
中文名称： 核受体亚家族1组H成员4抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human预测
交叉反应：： Cow
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： NR1H4
别名： Bile Acid Receptor NR1H4, BAR, FXR, Farnesoid X activated receptor, Farnesoid X receptor, Farnesoid X-activated receptor, Farnesol receptor HRR 1, Farnesol receptor HRR-1, Farnesol receptor HRR1, FXR, HRR 1, HRR1,NR1H4_HUMAN, Nuclear receptor subfamily 1 group H member 4, Retinoid X receptor interacting protein 14, Retinoid X receptor-interacting protein 14, RIP 14, RIP14, RXR interacting protein 14, RXR-interacting protein 14
背景说明： Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid, deoxycholic acid and allocholic acid. Plays a essential role in BA homeostasis through the regulation of genes involved in BA synthesis, conjugation and enterohepatic circulation. Also regulates lipid and glucose homeostasis and is involved innate immune response. The FXR-RXR heterodimer binds predominantly to farnesoid X receptor response elements (FXREs) containing two inverted repeats of the consensus sequence 5'-AGGTCA-3' in which the monomers are spaced by 1 nucleotide (IR-1) but also to tandem repeat DR1 sites with lower affinity, and can be activated by either FXR or RXR-specific ligands.
Swiss Prot： Q96RI1
Gene ID： 9971
亚细胞定位： Nucleus
免疫原： A synthetic peptide of human NR1H4
Public Immunogen Range： 250-300/486aa
理论分子量： 56/49kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。